Chloride Channels - Lysosomes Recordings
Port-a-Patch data and applications:
Data are taken from Schieder M. et al., The Journal of Biological Chemistry, 2010, 285(28), 21219-21222.
Typical chloride currents in four isolated lysosomes.Chloride currents were determined as difference currents between IV curves recorded in the absence and presence of extralysosomal high (64 mM) Cl-. On the left a sketch is illustrating the methodology.