Prof. Dr. Carlos Villalobos - Statement about the Port-a-Patch

   “We have used Nanion´s Port-a-patch for recording endogenous Icrac, the small calcium-release activated currents that are becoming very important in cell fate and cancer hallmarks. In addition, measurements were carried out in primary cultures of human, coronary, vascular-smooth muscle cells, a very difficult cell type to patch, and several normal and tumoral, epithelial cells. In the beginning I was very skeptical, because the currents are extremely small. However, the results were excellent and clear cut. It is possible to investigate the pharmacology and molecular biology of these channels during the phenotypic switches related to transdifferentiation, aging or tumorogenesis”.

Prof. Carlos Villalobos
University of Valladolid and Spanish Research Council (CSIC), Spain