• Port-a-Patch

    Smallest patch clamp setup in the world
  • Port-a-Patch

    Easy to learn - ideal for teaching
  • Port-a-Patch

    Records from cells, organelles and bilayers
  • Port-a-Patch

    First planar patch clamp device on the market
  • Port-a-Patch

    Ideal for internal solution exchange applications

2002 - Activity of single ion channel proteins detected with a planar microstructure

icon pap  Port-a-Patch publication in Applied Physics Letters (2002)

Fertig N., Klau M., George M., Blick R.H., Behrends J.C.

APL (2002) 81(25): 4865-67


We present recordings of currents mediated by single ion channel proteins obtained using planar, microstructured glass chips. In these chips, pores with diameters of 1–2 m are produced by iontrack etching and are used for patch clamping instead of using the classical micropipette. Our results represent success in using such devices to record from single channels in cell membranes. Theplanar chip greatly enhances the accessibility of the ion channel containing membrane and can serveas a workbench for experiments on single ion channels using combinations of patch clamp current recording with other single molecule techniques.

Download here

Back to Overview

We use cookies on our website. Some of them are essential for the operation of the site, while others help us to improve this site and the user experience (tracking cookies). You can decide for yourself whether you want to allow cookies or not. Please note that if you reject them, you may not be able to use all the functionalities of the site.