2011 - Cardiac Toxicity
Patchliner and Port-a-Patch book chapter in ADMET for Medicinal Chemists: A Practical Guide (2011)
Kettenhofen R., Schwengberg S.
ADMET for Medicinal Chemists: A Practical Guide, Edited by Katya Tsaioun and Steven A. Kates, John Wiley & Sons, Inc. (2011) 287 - 314
- cardiac toxicity and nonarrhythmic cardiac toxicity;
- preclinical models for assessment - of ion channel-related cardiotoxicity;
- pluripotent stem cell-derived cardiomyocytes - either from mouse or human origin, promising cellular models combining cell line advantages