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  • 210511 Nanion 917x516 2
  • SURFE2R 96SE Slide1

  • Research Ins]i[ghts: Nanion’s Transporter Webinar Series 2022
    08.09.2022 - Functional characterization and substrate binding kinetics of the Na+ cotransporters SGLT1 and GAT1

  • SURFE²R 96SE

    Fully automated data recording and analysis. 10,000 data points per day!

  • SURFE²R 96SE

    First high throughput instrument on the market for SSM-based electrophysiology

  • SURFE²R 96SE

    Finally high throughput label-free functional assays for transporters available

  • SURFE²R 96SE

    High signal amplification compared to patch-clamp: transport & binding assays

  • SURFE²R 96SE

    Turn-key system for efficient transporter protein analysis

PepT1 - Pharmacology of Losartan

Surfer N96 PepT1 Losarthan IC50 datacontrolIcon 96SE   SURFE2R N96 (a predecessor model of SURFE²R S96) data and applications:

Transport by PepT1 is inhibited by the kompetitive antagonist Losartan. When activated with 20 mM Gly-Gly, the IC50 of Losartan was 80.4 µM. Data were analysed with DataControl - the Analysis software tool for recordings on the SURFE2R N96 and SyncroPatch 96/ 384PE.

 

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