• SyncroPatch 384

    Next level versatility and flexibility
  • SyncroPatch 384

    True HTS and GigaOhm seals
  • SyncroPatch 384

    Your multi purpose instrument
  • SyncroPatch 384

    Powerful analysis software
  • SyncroPatch 384

    Assay flexibility via high tech
  • SyncroPatch 384

    Heating and cooling of solutions, cells and patch clamp sites

NaV1.7 - Accurate Voltage Clamp

SyncroPatch 384PE Nav17 CHO Anaxon 384 raw IV 2

 icon sp96   SyncroPatch 384PE (a predecessor model of the SyncroPatch 384) data and applications:
Cells were kindly provided by Anaxon AG.

CHO cells expressing NaV1.7 were used on the SyncroPatch 384PE  (a predecessor model of the SyncroPatch 384) with a success rate of > 90% for cells which have a seal resistance > 500 MΩ (see inset). A screenshot of the PatchControl 384 software showing current traces in response to a voltage step protocol and the corresponding current-voltage plot.

 

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