NaV1.5 - Late Current Analysis using the CiPA Protocol

   SyncroPatch 384/768 PE (a predecessor model of the SyncroPatch 384) data and applications:
Cells were kindly provided by Charles River.

Screenshots of the PatchControl 384 software showing Na_V1.5 current traces in response to the CiPA voltage step protocol, measured on the SyncroPatch 384PE (a predecessor model of SyncroPatch 384) using whole cell patch clamp methodology and single-hole chips. The Na_V1.5 late current was activated by the application of 60 nM ATX-II. The IC₅₀ value of Ranolazine of the late sodium current current was determined as 40.4 µM.

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