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  • SyncroPatch 384

    Next level versatility and flexibility

  • SyncroPatch 384

    True HTS and GigaOhm seals

  • SyncroPatch 384

    Your multi purpose instrument

  • SyncroPatch 384

    Powerful analysis software

  • SyncroPatch 384

    Assay flexibility via high tech

  • SyncroPatch 384

    Heating and cooling of solutions, cells and patch clamp sites

KV4.3 - Pharmacology of Metropolol Tartrate, using the CiPA Protocol

CiPA PE KV4.3 2icon sp96    SyncroPatch 384/768 PE (a predecessor model of SyncroPatch 384) data and applications:
Cells were kindly provided by Charles River.

Screenshots of the PatchControl 384 software showing KV4.3 current traces in response to the CiPA voltage step protocol, measured on the SyncroPatch 384PE (a predecessor model of SyncroPatch 384) using the whole cell patch methodology and single-hole chips. The IC50 value of Metropolol Tartrate was determined as 128 µM.

 

 

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