hASIC1a - "Pharmacology of human ASIC1a channels on Nanion’s SyncroPatch 384i"
SyncroPatch 384i (a predecessor model of the SyncroPatch 384) application note:
(1.4 MB)
Cells were kindly provided by Charles River.
Summary:
Acid-sensing ion channels (ASICs) are protongated ion channels which are highly sensitive to extracellular acidosis and are permeable to cations, predominantly Na+. They are members of the sodium-selective cation channels belonging to the epithelial sodium channel/degenerin (ENaC/DEG)family.
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