ClC-1 – Inhibition by 9-AC
SyncroPatch 384i (a predecessor model of SyncroPatch 384) data and applications:
Cells were kindly provided by Charles River.
Tail currents of ClC-1 expressed in CHO cells were inhibited by increasing concentration of 9-AC. A single concentration of 9-AC was added to each well and the concentration response curve constructed over multiple wells. The IC50 was calculated to be 6.3 µM for an average of 352 wells. The average current traces are also shown.