Mechanical Stimulation of Piezo1 Channels

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Cells were kindly provided by Prof. David Beech, University of Leeds, UK

HEK-hPiezo1, HEK-mPiezo1 and empty control HEK cells were activated in the same experiment by fluid shear stress: a small amount of solution was applied locally to the cell at 110µl/s pipetting speed in synch with a triggered recording of the voltage protocol.

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