Mechanical Stimulation of Piezo1 Channels
SyncroPatch 384 data and applications:
Cells were kindly provided by Prof. David Beech, University of Leeds, UK
HEK-hPiezo1, HEK-mPiezo1 and empty control HEK cells were activated in the same experiment by fluid shear stress: a small amount of solution was applied locally to the cell at 110µl/s pipetting speed in synch with a triggered recording of the voltage protocol.