• SyncroPatch 384

    Next level versatility and flexibility
  • SyncroPatch 384

    True HTS and GigaOhm seals
  • SyncroPatch 384

    Your multi purpose instrument
  • SyncroPatch 384

    Powerful analysis software
  • SyncroPatch 384

    Assay flexibility via high tech
  • SyncroPatch 384

    Heating and cooling of solutions, cells and patch clamp sites

Mechanical Stimulation of Piezo1 Channels

icon sp96   Mechanical Stimulation Piezo1SyncroPatch 384 data and applications:
Cells were kindly provided by Prof. David Beech, University of Leeds, UK

HEK-hPiezo1, HEK-mPiezo1 and empty control HEK cells were activated in the same experiment by fluid shear stress: a small amount of solution was applied locally to the cell at 110µl/s pipetting speed in synch with a triggered recording of the voltage protocol.

 

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