• SyncroPatch 384

    Next level versatility and flexibility
  • SyncroPatch 384

    True HTS and GigaOhm seals
  • SyncroPatch 384

    Your multi purpose instrument
  • SyncroPatch 384

    Powerful analysis software
  • SyncroPatch 384

    Assay flexibility via high tech
  • SyncroPatch 384

    Heating and cooling of solutions, cells and patch clamp sites

2022 - Dawn of a New Era for Membrane Protein Design

icon sp96 SyncroPatch 384PE (a predecessor model of the SyncroPatch 384 instrument) publication in BioDesign Research (2022)

Authors:
Sowlati-Hashjin S., Gandhi A., Garton M.

Journal:
BioDesign Research (2022) doi:10.34133/2022/9791435


Abstract: 

A major advancement has recently occurred in the ability to predict protein secondary structure from sequence using artificial neural networks. This new accessibility to high-quality predicted structures provides a big opportunity for the protein design community. It is particularly welcome for membrane protein design, where the scarcity of solved structures has been a major limitation of the field for decades. Here, we review the work done to date on the membrane protein design and set out established and emerging tools that can be used to most effectively exploit this new access to structures.


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