GABAA Receptor (a1b2g2) - On-set of response
SyncroPatch 96 (a predecessor model of SyncroPatch 384PE) data and applications:
With the SyncroPatch 96 currents can be recorded continuously during compound application. This, in conjunction with a solution exchange time of about 100 ms, makes the SyncroPatch 96 an excellent tool for investigations of ligand gated ion channels. In the data example, 10 μM GABA was added to a HEK293 cell expressing GABAA (α1β2γ2) receptors. The boxed trace shows a close up of the GABA-response.