• Vesicle Prep Pro

    First product on the market for automated preparation of solvent-free giant unilamellar vesicles (GUVs)
  • Vesicle Prep Pro

    GUVs are homogeneous in size - ideal for different applications

MscL - Pressure Clamp Experiments

p16 2 MscLicon pap   Port-a-Patch and   icon vpp   Vesicle Prep Pro data and applications:

The Port-a-Patch and the Suction Control Pro was used to study the effect of pressure on functional MscL protein reconstituted in GUVs. Using symmetrical KCl solutions, MscL gating was observed at -30 mBar and -60 mBar (holding potential + 30 mV), shown as outward currents in the data traces.

 

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