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    SyncroPatch 384i: HTS Automated Patch Clamp

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    SURFE²R 96SE: ラベルフリーのトランスポーターHTS

  • Dynamic Clamp: Patchliner

    Dynamic Clamp: Patchliner

  • 脂質二分子膜実験: Orbitシリーズ

    脂質二分子膜実験: Orbitシリーズ

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    CardioExcyte 96 SOL: 心筋の光ペーシング

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2017 - High throughput real-time measurement of electrogenic membrane transport driven by the SLC transporters PepT1 and OcT2

Icon 96SE   SURFE²R SE96 poster, Biophysics congress 2017  logo pdf   (1.8 MB)

 Abstract:

“Solid Supported Membrane (SSM) based electrophysiology” is an established method, developed at the Max-Plank-Institut, which allows to record low amplitude electrogenic events with a high amplification. The method allows real-time activity measurement of targets for which  onventional electrophysiology is unsuitable, like many electrogenic membrane transporters and pumps, or targets localized in intracellular or bacterial membranes.

Here, we present pharmacological and functional studies of different transporters and channels (PepT1, OCT2, NCX1, AChR alpha 7, mitochondrial F-type ATPase, XyIE, Channel rhodopsin 2), analyzed on the SURFE²R 96SE device.

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