Neurons (iPSC-derived) - TXX Block of Sodium Currents
Patchliner data and applications:
Cells were kindly provided by Cellular Dynamics.
A Block of Na+ current by increasing concentrations of TTX. Current was blocked by low nM concentrations of TTX indicating a TTX sensitive Na+ channel type expressed in this cell.
B Concentration response curve for TTX inhibition, IC50 = 4.9 nM (n =1).