2019 - Higher throughput in vitro cardiac contractility recordings under physiological mechanical conditions
FLEXcyte 96 white paper (2019)
Authors:
Stoelzle-Feix S., Juhasz K., Thomas U., Linder P., George M., Gossmann M.
Journal:
Nanion Self-publishing
Significance:
• Translatability of data obtained from hiPSC-CMs to human physiology is the subject of current scientific discussion
• Contractility data derived from hiPSC-CMs in an environment that reflects the mechanical properties of real human cardiac tissue in a higher throughput format (FLEXcyte 96) is physiologically relevant
• Example data on commercially available cell types with the FLEXcyte 96 system show a high degree of consistency with clinical data
