2019 - Higher throughput in vitro cardiac contractility recordings under physiological mechanical conditions

    FLEXcyte 96 white paper (2019)

Authors:
Stoelzle-Feix S., Juhasz K., Thomas U., Linder P., George M., Gossmann M.

Journal:
Nanion Self-publishing

Significance:

• Translatability of data obtained from hiPSC-CMs to human physiology is the subject of current scientific discussion

• Contractility data derived from hiPSC-CMs in an environment that reflects the mechanical properties of real human cardiac tissue in a higher throughput format (FLEXcyte 96) is physiologically relevant

• Example data on commercially available cell types with the FLEXcyte 96 system show a high degree of consistency with clinical data

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