• ClC-1

    Tail currents of ClC-1 expressed in CHO cells inhibited by increasing concentration of 9-AC on the SyncroPatch 384PE

  • Ec-ClC

    Typical Ec-ClC current response on the SURFE2R N1 (left) when chloride is applied to the sensor and the corresponding concentration response curve for chloride (right).

ClC-1 - Current-voltage plot

ClC 1 figure current voltage plot SP384 charles rivericon sp96   SyncroPatch 384i data and applications:
Cells were kindly provided by Charles River.

Activation of hClC-1 tail currents expressed in CHO cells recorded on the SyncroPatch 384i. A pre-pulse voltage step to +60 mV was followed by voltage steps from -120 mV to +80 mV for 300 ms (increasing in 20 mV steps) and the tail current was measured at the subsequent step to -100 mV. Out of a possible 384 wells, all 384 wells were used for the IV analysis

 

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