OmpF / OmpC - Outer Membrane Protein F and C
Outer membrane Channel Proteins, OMC family, β-Barrel and Porins Superfamily
OmpF and OmpC are two prokaryotic channel proteins which are located in the outer membrane and expressed amongst other bacteris by Escherichia coli, Salmonella typhimurium.
Topology and Function:
OmpF and OmpC forms pores that allow passive diffusion of small molecules across the outer membrane. Both are involved in osmoregulation: The widely distributed two-component system in bacteria, EnvZ/OmpR, respond to changes in envoronmental osmolality by regulating the expression of OmpF and OmpC the way that at lower osmolalities OmpC expression is less than OMPF expression.
Data and Applications