Currently open positions:


 

Nanion Technologies GmbH, Munich, Germany

1) Open PhD position

Nanion Technologies is a biotechnology company providing analytical instruments for electrophysiological research, drug discovery and safety screening. Nanion was founded in 2002 as a spin-off from the Center of Nanoscience (CeNS) at the Ludwig-Maximillian University (LMU) in Munich, and has expanded largely over the years counting today more than 100 employees worldwide. Nanion’s focus is automation and upscaling of electrophysiological techniques, with the core competence being high-throughput patch clamp electrophysiology. All Nanion devices are built and tested in-house in close collaboration of expert electrophysiologists, software and electrical engineers, and boasts a wide international network of universities as well as biotechnology and pharmaceutical industries. Nanion’s headquarter is located in Munich (Germany) and is well equipped with cell-culture and wet-lab facilities.

Nanion and the EVIDENCE ITN

As a partner in the EVIDENCE consortium, Nanion will contribute to characterizing the ion channel profile of native and artificial red blood cells (RBC)s. In the predecessor ITN, RELEVANCE, Nanion has established its technology as a robust tool to investigate Piezo1 channels in healthy and mutated RBCs (Rotordam et al., Haematologica, 2018). This approach will be extended to characterize the full ion channel profile of healthy RBCs (hKCa 3.1, Cav 2.1, NMDA receptors, chloride channels, etc.), and compare it to mutated, diseased or artificially generated RBC populations. The resulting functional characterization of a disease will provide the basis for the search for potential drug targets and help assess whether artificially generated RBCs are a viably substitute in anemias.

Candidate Profile

  • Candidates holding an MSc degree with a solid background in electrophysiology, cell biology, and/or pharmacology are encouraged to apply.
  • Experience in electrophysiology, especially patch clamp, and cell culture techniques is highly desirable.
  • Applicants will be enrolled in a PhD program, and must be willing to travel and work in collaborators laboratories.
  • Candidates with German nationality are excluded from applying for this specific position but are strongly invited to apply for positions with partners of the consortium outside Germany.
  • ITN eligibility criteria require that applicants have spent less than 12 months in the past 4 years in the host country (in Nanion’s case Germany).

Applications as well as informal enquires can please be sent to info@nanion.de


Nanion Technologies GmbH, Munich, Germany

2) Open PhD position

Nanion Technologies is looking for a passionate PhD candidate to work on functional characterization of neurotransmitter transporters using a novel electrophysiological approach.

Nanion Technologies is a biotechnology company providing analytical instruments for electrophysiological research, drug discovery and safety screening. Nanion was founded in 2002 as a spin-off from the Center of Nanoscience (CeNS) at the Ludwig-Maximillian University (LMU) in Munich and has expanded largely over the years counting today more than 100 employees worldwide. Nanion’s focus is automation and upscaling of electrophysiological techniques, with the core competence being high-throughput patch clamp electrophysiology. All Nanion devices are built and tested in-house in close collaboration of expert electrophysiologists, software and electrical engineers, and boasts a wide international network of universities as well as biotechnology and pharmaceutical industries. Nanion’s headquarter is located in Munich (Germany) and is well equipped with cell-culture and wet-lab facilities.

Nanion and the NeuroTrans ITN

The successful candidate will be part of the Marie Skłodowska-Curie Innovative Training Network (ITN) ‘NeuroTrans’ within the Horizon 2020 program of the European Commission. ‘NeuroTrans’ is a consortium of nine universities and five industrial entities in Germany, Portugal, Denmark, Austria, Italy, Netherlands, France and the United Kingdom. The position will be located at the Nanion Headquarters in Munich. It involves secondments at the Ludwigs-Maximilians University Munich and the University of Regensburg.

Aim of the study is the functional characterization of the neurotransmitter transporters SERT, DAT and GAT which are responsible for the transport of Serotonin, Dopamin and GABA within neurons. The main technique used will be solid-supported membrane-based electrophysiology, which is adopted in Nanion’s SURFE2R devices. The candidate will be also involved in further development of this technology to accelerate assay development for neurotransmitter transporter characterization.

Candidate Profile:

  • Candidates holding an MSc degree with a solid background in function and kinetics of transporters, membrane biophysics and/or electrophysiology are encouraged to apply.
  • Experience using transporter assays and/or electrophysiological techniques is highly desirable.
  • Applicants will be enrolled in a PhD program, and must be willing to travel and work in collaborators laboratories.
  • Candidates with German nationality are excluded from applying for this specific position but are strongly invited to apply for positions with partners of the consortium outside Germany.
  • ITN eligibility criteria require that applicants have spent less than 12 months in the past 4 years in the host country (in Nanion’s case

Start date should be summer 2020. The position is temporary and funded for 3 years. Applications as well as informal enquires can please be sent to info@nanion.de.


Unsolicited applications

As an expanding company we are always interested in hearing from skilled and creative people to join our team.
Please contact us for further information or send us a short CV (info@nanion.de)

 

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