08.05.2020: Live Cell Monitoring and Hypoxia using CardioExcyte 96
Live Cell Monitoring and Hypoxia
The oxygen (O2) concentration at normal atmospheric pressure is around 20–21% . The O2 levels in a healthy body ranges from 14% in the alveoli to 5% in peripheral tissues .
In pathological situations the O2 levels are lower (hypoxia), this especially occurs in tumor tissue, which is characterized by markedly low O2 levels that range from approximately 4% to a minimum of below 0.5%. Br J Radiol. 2014 Mar;87(1035):20130676.
In live cell monitoring assays, the O2 concentration is an important parameter that needs to be controlled, particularly when working with tumor cells or when analyzing the effects of hypoxia.
Source: Oxygen Conditions in Various Surroundings accessed 08.05.2020
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