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02.06.2020: Publication Alert - Could an Endo-Lysosomal Ion Channel be the Achilles Heel of SARS-CoV2?

Could an endo-lysosomal ion channel be the Achilles heel of SARS-CoV2?

Abstract

The ongoing SARS-CoV2 outbreak has developed into a global pandemic. Despite previous outbreaks of SARS-CoV and the related MERS-CoV in recent years, neither a vaccine nor any other medication for an effective treatment are currently available. Endo-lysosomal two-pore cation channels have now emerged as potential novel targets for SARS-CoV treatment.

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Did You Know: Ion Channels and their function in respiratory disease targets

The SARS-CoV-2 pandemic which emerged in late 2019, coupled with continued seasonal and pandemic influenza infections, has caused a significant problem for global public health and health systems worldwide. Antivirals and vaccines effective against these viruses are desperately needed in order to stem the pandemic and save lives.

A number of viroporins and ion channels are involved in viral infections and respiratory disorders.
Click here for a detailed look and references, inclusive of our latest application notes available for download - dealing with P2X3 and Chronic Cough

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