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26.07.2021 - Free Application Note - Assay Ready TRP-Channel Expressing Cells - a Flexible Tool to Screen for New Drug Candidates - acCELLerate & Assay.Works Application Note Application Note

Abstract:

Looking for new targets in pain and cancer therapy, the transient receptor potential chan-nels (TRP-channels) gained a lot of interest during the last decade. The ligand-gated calcium channels play an important role in the perception of pain and temperature and are often dysregulated in tumor tissues. They have become appealing targets for Drug Discovery. Re-combinant cell lines which stably express different TRP-channels have been successfully used for lead identification and compound profiling.

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