• Patchliner

    最高の実験柔軟性を誇るオートパッチ
  • Patchliner

    チップの自社内製造と厳格なQC
  • Patchliner

    10年以上のアッセイ系構築/サポート実績
  • Dynamite8

    Automated Dynamic Clamp
  • Patchliner

    マニュアルパッチの優位性を全て継承

Acetylcholine Receptor Alpha 7 - "Human a7 nicotinic Acetylcholine Receptor on the Patchliner "

icon pl   Patchliner application note:   logo pdf   (0.2 MB)
Cells were kindly provided by Galantos.

Summary:

The human a7 nicotinic acetylcholine receptor expressing cells (stable) from Galantos Pharma GmbH were tested on the Patchliner. Repeated stimulations with 100 μM nicotine were tested to validate the system. In a run, six out of eight cells could be measured. All six cells showed characteristic a7 currents. Average peak currents for the shown experiment were 0.9 ± 0.2 nA (n = 6) which is consistent with manual patch clamp results reported by Galantos Pharma.

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