• SURFE²R 96SE

    トランスポーターの完全自動記録/解析. 10,000データポイント/日!
  • SURFE²R 96SE

    市場初のSSM-電気生理学によるハイスループット評価系
  • SURFE²R 96SE

    ラベルフリーでトランスポーターのファンクショナルHTSアッセイ系を遂に実現
  • SURFE²R 96SE

    パッチクランプ法を超えるシグナル増幅率
  • SURFE²R 96SE

    トランスポータ解析のターンキーシステム

Amino Acid transporter - "Secondary screening assay for amino acid transporter inhibitors on the SURFE2R 96SE"

Icon 96SE   SURFE2R 96SE application note   logo pdf   (0.5 MB)

 Summary:

Na-dependent amino acid transporters play an essential role in the uphill transport of amino acids across the plasma membrane. In this study, a novel transporter target was used for which few specific pharmacological tools are available. The aim of this study was to establish a secondary screening assay using the direct electrophysiological measurement of the transporter to identify inhibitors. Using the SURFE2R 96SE, substrate specificity was determined and inhibitors could be identified. 

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