• SURFE²R N1

    簡便なオールインワン装置, アカデミックの教育ツールに最適
  • SURFE²R N1

    ラベルフリーでトランスポーターのファンクショナルHTSアッセイ系を遂に実現
  • SURFE²R N1

    パッチクランプ法を超えるシグナル増幅率
  • SURFE²R N1

    市場唯一のSSM-電気生理学システム
  • SURFE²R N1

    トランスポーター解析のターンキーシステム

Respiratory Chain Complex I and III - Current Over Mitochondrial Membrane

Surfer RC complexI III traceIcon N1   SURFE2R N1 data and applications:

In the respiratory chain Complex I and III, oxidation of NADH leads to transport of 4 protons across the membrane. The electrons are transferred to cytochrome c. Because of the electron leakage to oxygen, both complex are the main sites of production of harmful superoxide. In these experiments using the SURFE2R N1, application of 100µM NADH results in a current over the mitochondrial membrane, where Complex I and III are expressed.

 

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