• SyncroPatch 384

    Next level versatility and flexibility
  • SyncroPatch 384

    True HTS and GigaOhm seals
  • SyncroPatch 384

    Your multi purpose instrument
  • SyncroPatch 384

    Powerful analysis software
  • SyncroPatch 384

    Assay flexibility via high tech
  • SyncroPatch 384

    Heating and cooling of solutions, cells and patch clamp sites

hERG and Temperature Control

icon sp96   PE384 hERG TemperatureSyncroPatch 384 data and applications:
Cells were kindly provided by Charles River Chantest

Cardiac ion channels are recommended to be recorded at Phys. Temp. (ICH S7B Q&A. 2021). On the SyncroPatch 384, measurement site, cells and solutions can be accurately temperature controlled – in the presence of physiological temperatures the hERG current kinetic is changed to a larger slope and higher amplitude.


 

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