• Vesicle Prep Pro

    有機溶媒フリーで巨大単層ベシクル(GUV)を自動調製可能な市場初のシステム
  • Vesicle Prep Pro

    均一サイズのリポソームを自動調製 - 多様なアプリケーション

2018 - Phase partitioning, solvent-switchable BODIPY probes for high contrast cellular imaging and FCS

icon vpp   Vesicle Prep Pro publication in New Journal of Chemistry (2018)

Authors:
O’Connor D. Byrne A., Dolana C., Keyes T.E.

 

Journal:
New Journal of Chemistry (2018) doi.10.1039/C7NJ04604A


Abstract:

Lipophilic BODIPY fluorphores, in which the BODIPY core bears pendant dipyrido[3,2-a:2′,3′-c]phenazine (Dppz) or naphthyridyl and cholesterol substituents were designed and prepared as lipid probes for both liposomes and live cell imaging. The probes are non-emissive in water but permeate both GUV and live cell membranes and provide high contrast fluorescence and lifetime imaging of membranous structures and lipid droplets in cells and are suitable for FCS measurements on lipid membranes.


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