When: 15.02. - 19.02.2025

Venue: P1201 S. Figuero Street. Los Angeles, California 90015
Go to the Conference website here

Visit us at booth #509!

Nanion´s exhibitor presentation

When: Monday, February 17, 2025

Time: 11:30 AM - 1:00 PM PST

Location: Room 404AB

Session: Novel Insights into Ion Channel and Transporter Research

Join us for a captivating session at BPS 2025 on "Novel Insights into Ion Channel and Transporter Research: From Silent Translocation to Deep Learning Tools," which will highlight the latest advancements in ion channel and transporter assays, leveraging deep learning and novel electrophysiological techniques.

Featured presentations:

1. Leveraging Deep Learning Tools to Design hASIC1a Modulators
Speaker: Janina Sörmann, University of Copenhagen
Discover how deep learning is revolutionizing stroke therapy by enabling the design of potent, selective inhibitors for acid-sensing ion channels (ASICs). Dr. Sörmann will unveil novel miniproteins designed with AI tools and validated using the SyncroPatch 384 system, offering high efficacy and broad accessibility.

2. Benefits of SSME for the Investigation of the Lysosomal Ion Channels TMEM175, TPC2, and TRPML1
Speaker: Rocco Zerlotti, Nanion Technologies
Explore how Solid-Supported Membrane Electrophysiology (SSME) reveals functional insights into lysosomal channels such as TMEM175, TPC2, and TRPML1. Learn how the SURFE²R 96SE platform enhances understanding of ion permeability and channel modulation, complementing traditional patch-clamp techniques.

3. Integrated Optical and Electrical Techniques for Investigating Unsupported Lipid Bilayer Dynamics at the Single-Molecule Level
Speaker: Dan Burden, Wheaton College
Dive into a novel platform for studying biomolecule translocation across lipid bilayers at the single-molecule level. Dr. Burden will showcase the MECA platform, which combines optical and electrical measurements to detect electrically silent events, providing unparalleled insights into membrane dynamics and protein-lipid interactions.

Join us to explore how Nanion’s advanced technologies are driving new discoveries in electrophysiology and expanding the frontiers of ion channel and transporter research.

Visit us at the poster sessions

Sunday, February 16^th

Poster 1: Light-induced action potentials and STEM-cell derived sensory Neurons: An automated patch clamp investigation
Presenting author: Ali Obergrussberger
Location: West Exhibit Hall
Poster Session Title: Voltage-Gated Na Channels
Poster Board Number: B337

Poster 2: Block of voltage- and ligand-gated ion channels by toxins using automated patch clamp - A detection tool?
Presenting author: Ali Obergrussberger
Location: West Exhibit Hall
Poster Session Title: Voltage-Gated Na Channels
Poster Board Number: B343

Monday, February 17^th

Poster 3: Functional characterization of lysosomal channels TMEM175 and TPC2 using solid supported membrane-based electrophysiology
Presenting author: Rocco Zerlotti
Location: West Exhibit Hall
Poster Session Title: Ion Channels, Pharmacology, and Disease I
Poster Board Number: B402

Poster 4: Investigating the effect of temperature and trafficking modulator on hERG current using high throughput automated patch clamp
Presenting author: Søren Friis
Location: West Exhibit Hall
Poster Session Title: Voltage-Gated K Channels II
Poster Board Number: B329

Tuesday, February 18^th

Poster 5: Quantitative and mechanistic analysis of protein membrane pore formation o a high-throughput electrophysiology platform
Presenting author: Tobias Ensslen
Location: West Exhibit Hall
Poster Session Title: Voltage-Gated Na Channels
Poster Board Number: B103

Drug Discovery for Ion Channels XXV Satellite Meeting

Date: Friday, February 14, 2025
Time: 8:00 AM - 5:15 PM PST
Location: Room 107AB, Los Angeles Convention Center

Pre-registration deadline: January 10, 2025

This event is the perfect opportunity to explore cutting-edge innovations in ion channel drug discovery, from high-throughput automated electrophysiology to groundbreaking techniques and instrumentation.

Topic of sessions include:

• Insights into ion channel biology
• Innovative targeting approaches
• Emerging therapeutic applications
• Novel modulation strategies

Connect with leading experts, explore new technologies, and discuss the future of drug discovery for ion channels. Learn more about the satellite meeting by visiting the conference site

More updates about our activities at BPS 2025 will follow up in the next weeks.