Bettina Lickiss for BioTechniques
Showcased at ELRIG 2023. the focus of the discussion was on the innovative AtlaZ platform for live-cell analytics, utilizing electrical impedance spectroscopy with gold electrodes in a 96-well plate. This technology allows real-time analysis of diverse cellular responses, offering a high-throughput advantage across six 96-well plates simultaneously. The platform's versatility encompasses the real-time assessment of cell adhesion, proliferation, cytotoxicity, G-protein coupled receptor signaling, morphology, and barrier function.
The interview focused on the notable findings from the platform's testing, highlighting the successful ratio-dependent cancer cell killing by CAR-T cells and the concentration-dependent cardiotoxic effects of doxorubicin on a cardiac phenotype cell line. The AtlaZ platform emerged as a time-efficient and powerful tool, capable of conducting multiple analyses simultaneously and catering to a broad spectrum of research projects.