Automated patch clamp revolutionizes the patch clamp technique making it easier to use and increasing throughput. Automated patch clamp uses a planar borosilicate glass chip rather a fine glass pipette used in conventional patch clamp. The planar glass chip contains a small hole and suction is used from underneath to attract a cell to the hole and form a good seal between the glass and the cell membrane. Electrical currents are measured in the same way in automated and conventional patch clamp and the data quality is comparable between the two techniques. Throughput is increased by recording multiple cells simultaneously and applications such as exchanging the internal recording solution are possible.
Whether you are researching channelopathies, screening compound libraries, investigating biophysical properties and stimuli of ion channels, or doing routine cardiac safety screening, Nanion offers the right automated patch clamp instrument for you. With our range of throughput capabilities, unprecedented flexibility, outstanding quality and world-renowned customer support, you can be rest assured that you will make the right choice.