Accelerating transporter research
Would you like to feel the easiness of transporter research with an instrument specially designed for the measurements of electrogenic transporters?
The SURFE2R N1 is made to bring sensitivity, speed, and easiness into your transporter research. No need for harsh radiolabeled compounds, time-consuming protocols, or worries about missing transporter currents due to their small amplitude.
We are giving you the opportunity to receive a SURFE2R N1 for 6 months in your lab, including consumables and assay development support, completely free of charge.
Why should you apply?
What will
you do?
SURFE2R N1 enables comprehensive functional characterization of electrogenic membrane transport in real-time, offering heightened sensitivity and temporal resolution. It allows recordings from diverse membranes, including isolated membrane vesicles from native tissues or cultured cells, organellar membranes, and transporters reconstituted into proteoliposomes.
If you are looking for a sensitive instrument to measure small transporter currents, as those expected from secondary transporters, and want to study the function and inhibition of secondary transporters in a native-like environment without using radioligands and incease the speed and throughput of your research - this grant is for you!
SURFE2R N1
Product sheet
Winners 2024: their story
In 2024, we were thrilled to receive an outstanding selection of applications for the SURFE2R N1 instrument grant. The quality of proposals made it a tough decision for our judges, but ultimately, two exceptional projects stood out. Congratulations to both winners!
We are excited to support their research and look forward to seeing their innovative work unfold.
"Dissecting the molecular determinants of membrane transport protein stability in membranes"
Dr. Janice Robertson's research group at Washington University School of Medicine in St. Louis has been awarded the instrument grant for North America. They will use the SURFE2R to gain a fundamental and comprehensive understanding of what defines the stability of ion channels and transporters, as well as to identify new mechanisms of therapeutic modulation.
Watch the moment Janice discovered their proposal had been successful:
"Modulators of Drug Transporter Dynamics for Adjunct Therapies"
Dr. Chloé Martens' lab at the Université Libre de Bruxelles has been awarded the instrument grant for Europe. Their project focuses on identifying and designing modulators that either block or accelerate drug transport by influencing the conformational switching of transporters.
Watch the moment Chloé discovered their proposal had been successful:
Previous winners: their story
Success stories
Offering SURFE2R N1 research grants has become a tradition at Nanion, lasting since 2018. Many labs have benefited from this opportunity, and ultimately obtained their own systems.
Read the success stories of our previous SURFE2R N1 grant winners and learn how SURFE2R N1 accelerated their research!
How do I apply?
Applications are now closed!
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Curious about what the SURFE2R N1 could do for your research?
"A SURFE2R will allow us to perform high-throughput experiments using multiple non-labeled compounds. With the SURFE2R setup we will be able to characterize the currents and kinetic parameters of diverse secondary transporters and pre-select inhibitory compounds that later will be studied using in vivo assays on bacterial pathogens"
School of Medicine
Chicago, USA
“We wanted to characterize the electrophysiological characteristics of our new family of transporters to find out properties such as Km and Vmax of the substrate, and ideally to screen a set of substrates for transporter activity. Electrophysiology with the SURFE²R N1 platform worked right away. We saw very robust currents in our pilot experiments during the initial training session on the instrument.”
University of Michigan
Michigan, USA
University of Bern
Bern, Switzerland
Questions?
Contact our specialist Dr. Cecilia George (HQ Senior Sales Manager SURFE2R / Senior Scientist ). Cecilia and the rest of the SURFE2R N1 grant team. We are delighted to help you:
SURFE2R_Grant@nanion.de
or connect via LinkedIn
