Just like the SURFE2R N1, the SURFE2R 96SE employs solid supported membrane (SSM)-based electrophysiology to resolve small currents of transporters and pumps but elevates the throughput to the next level by parallelization of 96 measurements. The transporter samples are added to gold-coated sensors in a standard 96 well-plate format. To further reduce the user's workload, most sensor coating steps can be done by the SURFE2R 96SE itself. Any substrate can be added to activate the transporter. The resulting transport or binding currents will be detected and analyzed accordingly. The process from sensor preparation and measurement to data analysis is fully automated.
The SURFE2R 96SE is preferred over the SURFE2R N1 when a high throughput environment is needed. This is the case, e.g. for compound or transporter screening projects. The SURFE2R 96SE is also suitable to increase throughput for basic research. Data generation is approximately 100 times faster compared to the SURFE2R N1.
The SURFE2R 96SE is the only commercially available platform for higher throughput solid supported membrane (SSM) -based electrophysiology on the market.
Contact our specialist Dr. Maria Barthmes (Product Manager of the SURFE2R product family). Maria is delighted to help you:
Maria.Barthmes@nanion.de
or call: +49 89 2190 95-068
or connect via LinkedIn
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