GABAA Receptor - Currents in iCell Neurons
Patchliner data and applications:
Cells were kindly provided by Cellular Dynamics.
Activation of GABAA receptor currents by 30 μM GABA and partial block of the current response by 1 μM bicuculline. Bicuculline was pre-applied for at least 30 s before co-application with GABA (30 μM). Approximately 50% of the current was blocked by 1 μM bicuculline.
![27.06.2022: Publication Alert - Discovery of agonist–antagonist pairs for the modulation of Ca [2]+ and voltage-gated K+ channels of large conductance that contain beta1 subunits](/images/Images_tiff_jpg_png/Corporate_Blog_Press_Releases/220627_blog_image_Discovery%20of%20agonist–antagonist%20pairs%20for%20the%20modulation%20of%20Ca2+%20and%20voltage-gated%20K+%20channels%20of%20large%20conductance%20that%20contain%20beta1%20subunits.jpg)
