CaV1.2 - Current Voltage Relationship

   SyncroPatch 384PE (a predecessor model of SyncroPatch 384) data and applications:
Cells kindly provided by Charles River.

Ca_V1.2 expressed in CHO cells recorded on the SyncroPatch 384PE (a predecessor model of SyncroPatch 384). A The screenshot shows the data acquisition and analysis software used on the SyncroPatch 384PE. The online analysis values are shown for a current-voltage experiment. B The raw traces from an example cell elicited by depolarizing steps from -60 mV to 40 mV in 10 mV increments from a holding potential of -80 mV are shown. C The normalized current-voltage plot for an average of 272 cells. A Boltzmann equation fit revealed a V_0.5 of activation of -4.8 mV.

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