hERG - Application of Dofetilide
Port-a-Patch mini data and applications:
Cells were kindly provided by SB Drug Discovery.
Raw data traces of hERG (expressed in HEK cells) in control solution and in the presence of increasing concentrations of Dofetilide (top). IC50 concentration response curve for an average of 3 cells is shown revealing an IC50 of 161 ± 12 nM.