2021 - Long noncoding RNA VENTHEART is required for cardiomyocyte specification and function
CardioExcyte 96 pre-print publication in bioRxiv (2021)
Authors:
Dashi A., Tan W.L.W., Anene-Nzelu C.G., Pan B., Ilmari A.M., Tiang Z., Hartman R.J.G., Stenzig J., Wei H., Gao Bin C., Ackers-Johnson M.A., Lim B., Walentinsson A., Iyer V.V., Jonsson M.K.B., Foo R.S.
Journal:
bioRxiv (2021) doi: 10.1101/2021.02.01.429136
Abstract:
Long noncoding RNAs (lncRNAs) control cardiac gene expression during heart development and disease. It is accordingly plausible for the same lncRNA to regulate both cardiac development, as well as play a role in adult heart disease progression. lncRNA regulators of early cardiomyocyte (CM) lineage commitment have been identified and characterised, however those controlling later CM specification remain unknown.