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Publications

icon pap   Port-a-Patch,   icon pl   Patchliner and   icon sp96   SyncroPatch 96 publication in Expert Opinion on Drug Discovery (2012)
HTS techniques for patch clamp-based ion channel screening - economy and advances.

icon pl   Patchliner and   icon pap   Port-a-Patch publication in Journal of Biological Chemistry (2011)
Automated Patch Clamp on mESC-Derived Cardiomyocytes for Cardiotoxicity Prediction.

icon pl   Patchliner and   icon pap   Port-a-Patch book chapter in ADMET for Medicinal Chemists: A Practical Guide (2011)
Chapter: Cardiac Toxicity.

icon pap   Port-a-Patch,   icon pl  Patchliner and   icon sp96   SyncroPatch 96 publication in Frontiers in Pharmacology (2011)
State-of-the-art automated patch clamp devices: heat activation, action potentials, and high throughput in ion channel screening.

icon pl  Patchliner publication in General Physiology and Biophysics (2011)
Pharmacological studies of Cav3.1 T-type calcium channels using automated patch-clamp techniques.

icon pl   Patchliner and   icon sp96   SyncroPatch 96 publication in Frontiers in Pharmacology (2011)
Automated electrophysiology makes the pace for cardiac ion channel safety screening.

icon pap  Port-a-Patch,   icon pl   Patchliner and   icon sp96   SyncroPatch 96  publication in Future Medical Chemistry (2010)
Renaissance of ion channel research and drug discovery by patch clamp automation.

icon pap  Port-a-Patch publication in Proc. Natl. Acad. Sci. USA. (2010)
Multiplexed transposon-mediated stable gene transfer in human cells.

icon pap  Port-a-Patch and   icon pl   Patchliner publication in Lonza Resource Notes (2010)
Cor.At Cardiomyocytes: Primary-like Cardiomyocytes for Manual and Automated Electrophysiological Screening.

icon pl  Patchliner publication in Frontiers in Pharmacology (2010)
Propranolol blocks cardiac and neuronal voltage-gated sodium channels.

icon pap  Port-a-Patch and   icon pl   Patchliner publication in Combinatorial Chemistry & High Throughput Screening (2009)
Port-a-Patch and Patchliner: High fidelity electrophysiology for secondary screening and safety pharmacology.

icon pl  Patchliner publication in Frontiers in Molecular Neuroscience (2009)
High throughput techniques for discovering new glycine receptor modulators and their binding sites.

icon pl  Patchliner publication in Nature Protocols (2009)
Robotic multiwell planar patch-clamp for native and primary mammalian cells.

 
 
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