Publications
SyncroPatch 384 publication in The Journal of Physiology (2021)
The suitability of high throughput automated patch clamp for physiological applications
SyncroPatch 768PE (a predecessor model of the SyncroPatch 768i instrument) publication in The Journal of Clinical Investigation (2020)
Striatal Kir2 K+ channel inhibition mediates the antidyskinetic effects of amantadine
SyncroPatch 384i publication (Supplement) in Neurology (2020) 94(15):5571
Augmenting BK Channel Function as Therapy for Spinocerebellar Ataxia (SCA) (5571)
SyncroPatch 384PE (a predecessor model of the SyncroPatch 384i instrument) pre-publication in BioRxiv (2020)
Computer modeling of whole-cell voltage-clamp analyses to delineate guidelines for good practice of manual and automated patch-clamp.
SyncroPatch 384PE (a predecessor model of the SyncroPatch 384i) publication in Philosophical Transactions of the Royal Society A (2020)
Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage-clamp experiments.
SyncroPatch 768PE (a predecessor model of the SyncroPatch 768i) pre-publication in bioRxiv (2020)
GS-967 and Eleclazine Block Sodium Channels in Human Induced Pluripotent Stem Cell-derived Cardiomyocytes.
SyncroPatch 384PE and
Patchliner article in Nature Scientific Reports (2020)
Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells.
SyncroPatch 384PE and
Patchliner article in Toxicology and Applied Pharmacology (2020)
A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm.
SyncroPatch 384PE Publication in PNAS (2020)
Mechanism and site of action of big dynorphin on ASIC1a.
SyncroPatch 96 (a predecessor model of the SyncroPatch 384i) Publication in Journal of Vascular Research (2020)
Novel Expression of GABAA Receptors on Resistance Arteries That Modulate Myogenic Tone.
SyncroPatch 384PE publication in SLAS Discovery (2020)
Application of High-Throughput Automated Patch-Clamp Electrophysiology to Study Voltage-Gated Ion Channel Function in Primary Cortical Cultures..
SyncroPatch 384PE publication in Cardiovascular Research (2019)
Pharmacological activation of IKr in models of long QT Type 2 risks overcorrection of repolarization.
SyncroPatch 768PE Publication in Cell Chemical Biology (2019)
Development of Photocrosslinking Probes Based on Huwentoxin-IV to Map the Site of Interaction on Nav1.7.
SyncroPatch 384PE,
Patchliner and
Port-a-Patch review article in Current Protocols in Pharmacology (2019)
Role of High‐Throughput Electrophysiology in Drug Discovery.
SyncroPatch 384PE (a predeccessor model of the SyncroPatch 384i) publication in Annals of Clinical and Translational Neurology (2019)
Functional consequences of a KCNT1 variant associated with status dystonicus and early‐onset infantile encephalopathy.
SyncroPatch 384PE Pre-publication in bioRxiv Biology (2019)
High-throughput reclassification of SCN5A variants.
SyncroPatch 768PE Publication in Annals of Neurology (2019)
Spectrum of KV2.1 Dysfunction in KCNB1‐Associated Neurodevelopmental Disorders.
SyncroPatch 384PE publication in Heart Rhythm (2019)
High-throughput phenotyping of heteromeric human ether-à-go-go-related gene potassium channel variants can discriminate pathogenic from rare benign variants.
SyncroPatch 768PE Pre-Publication in BioRxiv (2019)
High Throughput Characterization of KCNB1 Variants Associated with Developmental and Epileptic Encephalopathy.
SyncroPatch 384PE publication in Toxins (2019)
Chemical Synthesis, Proper Folding, Nav Channel Selectivity Profile and Analgesic Properties of the Spider Peptide Phlotoxin 1