• GABAA a1b2g2

    Concentration dependent activation and desensitization of GABAA (α1β2γ2) receptors by application of 1, 3 and 10 μM GABA as measured on the Port-a-Patch)

GABAA Receptor - Currents in iCell Neurons

GABA Bicuculline neurons

icon pl   Patchliner data and applications:
Cells were kindly provided by Cellular Dynamics.

Activation of GABAA receptor currents by 30 μM GABA and partial block of the current response by 1 μM bicuculline. Bicuculline was pre-applied for at least 30 s before co-application with GABA (30 μM). Approximately 50% of the current was blocked by 1 μM bicuculline.

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