• GABAA a1b2g2

    Concentration dependent activation and desensitization of GABAA (α1β2γ2) receptors by application of 1, 3 and 10 μM GABA as measured on the Port-a-Patch)

GABAA Receptor - Modulator Diazepam

Diazepam

 icon sp96   SyncroPatch 96 (a predecessor model of SyncroPatch 384PE) data and applications:

Shown is a raw current response of a HEK293 cell expressing GABAA receptors to initial exposure to GABA, followed by joint exposure to GABA and diazepam (as indicated). Solutions were  stacked (layered) in the pipette to achieve brief exposure times.

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