• GABAA a1b2g2

    Concentration dependent activation and desensitization of GABAA (α1β2γ2) receptors by application of 1, 3 and 10 μM GABA as measured on the Port-a-Patch)

GABAA Receptor (a1b2g2) - On-set of response

Gaba and close up bea

icon sp96   SyncroPatch 96 (a predecessor model of SyncroPatch 384PE) data and applications:

With the SyncroPatch 96 currents can be recorded continuously during compound application. This, in conjunction with a solution exchange time of about 100 ms, makes the SyncroPatch 96 an excellent tool for investigations of ligand gated ion channels. In the data example, 10 μM GABA was added to a HEK293 cell expressing GABAA (α1β2γ2) receptors. The boxed trace shows a close up of the GABA-response.

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