GlyR a1 | Glycine Receptor Alpha 1
Glycine receptors (cys-loop receptors)
There are presently four known isoforms of the α-subunit (α1-4) of GlyR that are essential to bind ligands (GLRA1, GLRA2, GLRA3, GLRA4) and a single β-subunit (GLRB).
As typical cys-loop receptors, glycine receptor subunits contain four transmembrane spanning domains TM1-TM4. Five subunits form a pore, homomeric and heteromeric combinations are possible.
Data and Applications