OmpF / OmpC - Outer Membrane Protein F and C
Family:
Outer membrane Channel Proteins, OMC family, β-Barrel and Porins Superfamily
Description:
OmpF and OmpC are two prokaryotic channel proteins which are located in the outer membrane and expressed amongst other bacteris by Escherichia coli, Salmonella typhimurium.
Topology and Function:
OmpF and OmpC forms pores that allow passive diffusion of small molecules across the outer membrane. Both are involved in osmoregulation: The widely distributed two-component system in bacteria, EnvZ/OmpR, respond to changes in envoronmental osmolality by regulating the expression of OmpF and OmpC the way that at lower osmolalities OmpC expression is less than OMPF expression.
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