TRPM3 - Positive modulation

TRPM3 PS C Dataicon pl   Patchliner data and applications: 
Cells were kindly provided by Prof. Thomas Voets, KU Leuven, Belgium.

A Current responses to a voltage ramp protocol from -150 mV to 150 mV over 200 ms in response to 100 μM pregnenolone sulphate (PS) and in combination with increasing concentrations of compound C. B Current responses elicited by PS, enhancement by 30 μM compound C and block of the current by co-application of antagonist (10 μM).

 

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