Nanion 运营日志

 

14.05.2020: 新发表论文预览 - 从分子水平评价抗癌药物的作用

从分子水平评估抗癌药物作用的非标定生物电化学方法

Abstract

Cancer is a multifactorial family of diseases that is still a leading cause of death worldwide. More than 100 different types of cancer affecting over 60 human organs are known. Chemotherapy plays a central role for treating cancer. The development of new anticancer drugs or new uses for existing drugs is an exciting and increasing research area. This is particularly important since drug resistance and side effects can limit the efficacy of the chemotherapy. Thus, there is a need for multiplexed, cost-effective, rapid, and novel screening methods that can help to elucidate the mechanism of the action of anticancer drugs and the identification of novel drug candidates. This review focuses on different label-free bioelectrochemical approaches, in particular, impedance-based methods, the solid supported membranes technique, and the DNA-based electrochemical sensor, that can be used to evaluate the effects of anticancer drugs on nucleic acids, membrane transporters, and living cells. Some relevant examples of anticancer drug interactions are presented which demonstrate the usefulness of such methods for the characterization of the mechanism of action of anticancer drugs that are targeted against various biomolecules.

Download the Publication

Don't forget to register for our Transporter Webinar on the 19th of May (Tuesday).
Join live or register and receive an On-Demand Copy.

"INSIGHTS AND NEW APPROACHES IN TRANSPORTER CHARACTERIZATION - SURFE²R N1"

Date: 19. May 2020

Time: 4:00 PM CET / 10:00 AM EDT

Register here 


Speakers:

Prof. Dr. Camilo Perez (Head of Research Group - BIOZENTRUM, University of Basel, Switzerland)

Nathan Thomas (5th Year PhD, University of Wisconsin-Madison [Dr. Henzler-Wildman's lab])

Dr. Maria Barthmes (Product Manager, Nanion Technologies)

返回总览

We use cookies on our website. Some of them are essential for the operation of the site, while others help us to improve this site and the user experience (tracking cookies). You can decide for yourself whether you want to allow cookies or not. Please note that if you reject them, you may not be able to use all the functionalities of the site.