Nanion 运营日志


19.10.2020 - Poster - Mechanical Stimulation in a 2D High-Throughput Contractility System

Mechanical Stimulation in a 2D High-Throughput Contractility System Induces Functional Changes in Human Induced Pluripotent Stem Cell Derived Cardiomyocytes

The use of human induced pluripotent stem cell-derived cardiomyocytes (hiPSCCMs) to assess efficacy and cardiac safety of new drug candidates continues to increase. In this context, a new 2D high-throughput system, FLEXcyte 96, allows for contractility measurements of cells cultured in a more physiological environment, reflecting the mechanical conditions of the native human heart. This study aims to show the influence of mechanical stimulation on functional behavior of hiPSC-CMs. This aspect is of particular importance, as mechanical load acts as crucial growth regulator in the developing heart.

Download the Poster



We use cookies on our website. Some of them are essential for the operation of the site, while others help us to improve this site and the user experience (tracking cookies). You can decide for yourself whether you want to allow cookies or not. Please note that if you reject them, you may not be able to use all the functionalities of the site.