• CardioExcyte 96

    结合阻抗与类MEA记录
  • CardioExcyte 96

    用于心脏安全筛选
  • CardioExcyte 96

    下一代非标记细胞分析
  • CardioExcyte 96

    直观的数据分析&心律失常检测
  • CardioExcyte 96

    提供可用于成像的透明板

Cardiac Ion Channels - Pharmacology of Sotalol

CiPA PE CE Pharmacology SotalolIcon CE    CardioExcyte 96 and   icon sp96   SyncroPatch 384PE data and applications:
Cells were kindly provided by Charles River and Cellular Dynamics.

The image on the left hand side displays the results of the blocking effect of Sotalol on hERG. The result is in good agreement with manual patch clamp data (Crumb et al., 2016). The compound induced arrhythmia when iPSC-CM were exposed to a minimum concentration of 10 µM. Arrhytmic events were both detected in field potential recordings as well as in the impedance based contractility measurements.

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