• CardioExcyte 96

    结合阻抗与类MEA记录
  • CardioExcyte 96

    用于心脏安全筛选
  • CardioExcyte 96

    下一代非标记细胞分析
  • CardioExcyte 96

    直观的数据分析&心律失常检测
  • CardioExcyte 96

    提供可用于成像的透明板

Cardiomyocytes - Time-dependent effect of Pentamidine on Cor.4U cardiomyocytes

Icon CE   CardioExcyte Cor4U PentamidineCardioExcyte data and applications:
Cells were kindly provided by Axiogenesis.

Time-dependent effect of Pentamidine on Cor.4U cardiomyocytes. Pentamidine clinically causes acquired long QT syndrome, which is associated with prolonged QT intervals, tachycardias, and sudden cardiac arrest. Pentamidine delays terminal repolarization in human heart by acutely blocking cardiac inward rectifier currents. At the same time, it reduces surface expression of the cardiac potassium channel IKr/human ether à-go-go-related gene (hERG).
Insets: EFP raw traces and online analysis value FPDc in the presence of Pentamidine (10 µM) at different timepoints.

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