Kinase inhibitors – Chronic compound effects on cardiomyocytes
FLEXcyte 96 data and applications:
Cells were kindly provided by Cellular Dynamics.
Here Structural and/or functional toxicity of Kinase inhibitors Trametinib, Sorafenib, Nilotinib and A-674563 was investigated. Compound incubation time was 5 days.
During investigations of chronic effects it could take days and weeks until onset of adverse effects. The CardioExcyte and FLEXcyte technology and the consumables are perfectly suited for such studies.